|1 out of 3 seniors will develop Macular Degeneration.*|
|Zeaxanthin deficiency may be the very cause of AMD.*|
|Studies show increase daily intake of Zeaxanthin may stop or reverse AMD.*|
|Studies show Zeaxanthin may protect against Cataracts.*|
1 - Macular Degeneration happens in the Center of Vision.
2 - Zeaxanthin Carotenoid protects the Macula and Retina.
3 - Zeaxanthin makes up 75% of our vision protection.*
4 - As we age we become more deficient in Zeaxanthin.*
a. Zeaxanthin is very scarce in foods.
b. We have no available source of Zeaxanthin.
c. Eye formulas are deficient in Zeaxanthin.
d. Eye Doctors have no available source of Zeaxanthin.
5 - Clinical studies reflect a definite need for Supplementing Zeaxanthin.*
a. Zeaxanthin helps Lutein get absorbed in the eye.*
“It is logical that people can go blind from a deficiency of the very nutrient that is contained in 75 % of the center of the Macula and Retina”.
6 - Lutein is
active in protecting 65% of peripheral vision.
a. Lutein is present in many vegetables, unlike Zeaxanthin.
b. Eye Supplements may provide sufficient Lutein.
7 - Eye Exercise for Improved Vision
a. Turn eyes in every possible direction for 15 to 30 minutes.
b. TV commercials are a good time to exercise.
c. Many with poor vision gain 20-20 vision with eye exercise.
CLINICAL STUDIES #1 Center of Vision
1 - The following chart
shows why there is a
2 - This study recommends increased amounts of Zeaxanthin.
3 - Clinical studies reflect a need for supplementing 2 times
as much Zeaxanthin as Lutein.
1. There are reasons why Zeaxanthin may be more important than Lutein.
2. Zeaxanthin is deposited in a 2:1 ratio vs. Lutein in the center of the macula.
3. Zeaxanthin is
20 times less prevalent in a healthy
diet than Lutein;
4. Increased Zeaxanthin supplementation increases macular pigment density.
5. Zeaxanthin is rare in the diet and is preferentially taken up by the macula and deposited in the most crucial portion of the macula and Retina.
6. Zeaxanthin is deposited in the very center, at a ratio of 2:1 over Lutein.
7. It is critical that patients at risk for age-related macular degeneration and those diagnosed with AMD, receive the maximum beneficial amounts of Zeaxanthin to replenish the heart of the macula.
8. The above chart shows reason for supplementation.
9. Clinical studies show marked protection and/or improvement of vision from taking 20 mg of Zeaxanthin daily.
Extracting Zeaxanthin is a Manufacturing Problem
1. Both Lutein and Zeaxanthin come from the Marigold plant.
2. The natural extraction ratio is 20 parts of Lutein to 1 Zeaxanthin. (Ratio 20:1)
Conclusion: The Correct Balance for the body is 20 mg of Zeaxanthin to 10 mg of Lutein or a (Ratio of 2:1)
CLINICAL STUDY #2 NIH
Eye Disease Case-Control Study
The macula contains high levels of carotenoids; in fact, the yellow color gives the macula its name. Evidence suggests that two carotenoids, Zeaxanthin and Lutein play another role. They help filter blue light, which is especially harmful to photoreceptors. The lens and cornea filter out UV light, but cannot filter visible blue light. This light can contribute to AMD. Patients with low macular pigment densities are known to be more prone to developing AMD.
Zeaxanthin Supplements “increase macular
Zeaxanthin also protects:
a. Retina - Against photo damage to the Retina
b. Photoreceptors - Oxidation of the Photoreceptor Membrane
c. Macula - Blood Vessels that supply the macula.
Reduced Risk of AMD with Zeaxanthin Supplement
There was a statistically significant and apparently linear trend for a decreased risk of AMD with increasing amounts of carotenoids, specifically Zeaxanthin and Lutein, in the diet. Consumption of dark green, leafy vegetables and Orange peppers seems to help protect against AMD.
have also associated low carotenoid levels with cataracts.
The National Eye Institute is currently sponsoring a large study of
antioxidants, while recommending these 4 supplements of Zeaxanthin, Vitamin E,
Zinc and Lutein.
Dr. Abelson, an Associate Clinical Professor of Ophthalmology at the Harvard Medical School, consults in ophthalmic pharmaceuticals. "Eat food with high antioxidant levels, such as spinach, a good source of both vitamin E and Lutein, protects against cataract.
STUDY #3 Zeaxanthin and Lutein
Two increasingly promoted carotenoids make up the macular pigment, located in the center of the retina where the finest vision occurs. A study at Boston's Schepens Eye Research Institute in 1998 showed that elderly people with thicker macular pigment reacted to light more effectively. Advocates of these nutrients suggest that taking supplements of them will help you build a thicker pigment layer, preserving vision as you age.
STUDY #4 AMDF American Macular Degeneration Foundation "Saving sight through research and education"
1. "Macular degeneration is the leading cause of blindness affecting more Americans than cataracts and glaucoma combined".
2. Zeaxanthin is the dominant component within the central macula.
3. Zeaxanthin may Decrease Risk of AMD.
We are facing an epidemic. Millions
of unsuspecting Americans may go blind
from macular degeneration.
STUDY #5 Zeaxanthin Nutrition = Less Cataracts
Certain Nutrients Reduce Cataract Development
Nutrition linked to cataract formation
Eating Fruits and Vegetables May Preserve Vision
Certain Nutrients Reduce Cataract Development: The authors found that "those with the highest intake of Zeaxanthin and Lutein had a 22% decreased risk of
cataract extraction compared with those in the lowest."
Zeaxanthin is rare in foods, needing supplementation. Foods rich in Lutein include spinach, kale, and collard greens. The authors further state, "increasing frequency of intakes of spinach and kale, foods rich in Lutein, was associated with a moderate decrease in risk of cataract" and may "decrease the risk of cataracts severe enough to require extraction."
CATARACT RISK REDUCED
STUDIES #6 CATARACTS Zeaxanthin Research Update
Human eye cells
treated with Zeaxanthin and Lutein showed less damage
after being exposed to ultraviolet rays, the sunlight rays considered a
major contributor to cataracts. Cataracts occur when proteins in the
eye's lens begin to clump together, forming a milky cloud that obscures
vision. It is
thought that the more sunlight a person is exposed to in life,
the greater the risk for cataracts.
Researchers at Ohio State University in Columbus grew human lens cells
in a laboratory, then added Zeaxanthin, Lutein, vitamin E, or left the cells alone. The researchers then exposed the eye cells to ultraviolet (UV) radiation, in order to mimic the effect of sunlight. Lens cells mixed with Zeaxanthin and Lutein showed significantly less damage following UV-exposure than cells that had no shielding from antioxidants.. SOURCE: Journal of Nutrition, December 2004.
Macular carotenoids: Zeaxanthin and Lutein
The yellow color of the macula lutea is due to the presence of the carotenoid pigments zeaxanthin and lutein. No other major carotenoids including Beta-carotene or lycopene are found in this tissue.
against Blue Light damage to Retina.
2) Antioxidant for destroying free radicals in tissue of Retina.
3) Protects against Macular Degeneration.
4) Low Levels of Zeaxanthin and Lutein are Associated with Vision Loss (AMD).
5) (Zeaxanthin needs supplementing) Increased intake of foods containing Lutein may be effective in preventing AMD because macula accumulates Lutein.
STUDY #7 Wolfberry is rich in zeaxanthin dipalmitate, and is valued in Chinese culture for being good for vision.
Single-blinded, placebo controlled study
1 - 15 g/d WOLFBERRY Supplemented (3mg of Zeaxanthin)
2 - 29 days = plasma Zeaxanthin increased 250%
Zeaxanthin Study as little beadlets
1 - Long term of 1mg = plasma Zeaxanthin increased 400%
2 - Long term of 10mg = plasma Zeaxanthin increased 2000%
Long-term oral intake of 1 and 10 mg Zeaxanthin
as bead lets increases plasma Zeaxanthin concentrations
approximately 4- and 20-fold, respectively.
Evidence that all Lutein (E-3-dehydro) is formed from Zeaxanthin
Br J Nutr. 2005 Jan;93(1):123-30. Lycium barbarum L. is a small red berry known as Fructus lycii and wolfberry in the West, and Kei Tze and Gou Qi Zi in Asia.
STUDY #8 A research report in the Journal Ophthalmology 32% higher level of pigment in the eyes of age-related macular degeneration (AMD) patients, supplementation with Zeaxanthin and Lutein. Macular carotenoid levels decline with age, a stable low level after age 60 and AMD rise dramatically.
The research was led by Paul S. Bernstein, M.D., Ph.D., at the Dept of Ophthalmology and Visual Sciences, University of Utah. Bernstein is a Research to Prevent Blindness Sybil B. Harrington Scholar in macular degeneration research.
STUDY #9 CONSUMERS LABS - 19 EYE Formulas Tested "ATTENTION VIEWERS WITH EYESIGHT CONCERNS" "Zeaxanthin Deficiency" in Eye formulas CONSUMER LABS TESTING:
1) Zeaxanthin is “Extinct” or “Deficient” in eye formulas.
2) 1 formula had only 1/3 mg(.28) of Zeaxanthin.
3) 1 formula had only 1 mg of Zeaxanthin.
4) The rest had NO ZEAXANTHIN (of 13 published)
AGE-RELATED MACULAR DEGENERATION
Zeaxanthin and Lutein are members of the carotenoid family — a group of natural plant pigments that also includes beta-carotene and lycopene. They are unique in that they are the only carotenoids found in high concentration in the macula of the eye. Lutein is available from a wide variety of foods. Most adults in the U.S. consume less Zeaxanthin than the amount believed to lower their risk of macular degeneration. Consequently, dietary supplements are often used to
increase zeaxanthin, as well as Lutein levels.
Supplementing Zeaxanthin at age 40 is the best future AMD protection
1. 9 % of people over 40 have some form of macular degeneration.
2. 27% of people over 65 have macular degeneration.
3. 35% of people over 70 have macular degeneration
CATARACT PREVENTION -
1. Evidence shows Zeaxanthin and Lutein help prevent cataracts.
2. Evidence also shows a lower risk of colon and breast cancer.
* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. This information is nutritional in nature and should not be construed as medical advice. This notice is required by the Federal Food, Drug and Cosmetic Act.